Audio Playerhttps://media.ktoo.org/2017/05/170525HELICOPTER.mp300:0000:0000:00Use Up/Down Arrow keys to increase or decrease volume.Coastal Helicopters released a statement that its helicopter was returning about 6 p.m. Monday to Juneau when it ran into trouble on Herbert Glacier. The NTSB says that the AStar helicopter sustained major damage and was disabled.“My understanding is a second Coastal Helicopter was able to reach the site and were able to get the folks off of the glacier before nightfall,”said Clint Johnson, NTSB’s regional aviation chief in Anchorage. The Juneau-based charter company still is trying to retrieve its aircraft, he said. Coastal Helicopters operates out of Juneau International Airport and regularly ferries tourists to the ice fields about 20 miles north of Juneau. “What we understand is that this helicopter was operating in connection with a dog sledding excursion on the Herbert Glacier or in that area,” Johnson said. “We’re working very closely with Coastal Helicopters at this point right now to find out exactly what the circumstances were that led up to this accident and also what the extent of the injuries – if any.”No names have been released. Investigators say the company is fully cooperating with the NTSB.Share this story: Juneau | Search & Rescue | TransportationNTSB investigating helicopter crash on Herbert GlacierMay 25, 2017 by Jacob Resneck, KTOO Share:A May 22 crash involved an Airbus AStar 350 similar to this one flown by Coastal Helicopters of Juneau. (File photo by Jacob Resneck)The National Transportation Safety Board is investigating how and why a Juneau-bound helicopter ferrying tourists crashed during a glacier excursion. The pilot and six tourists were treated and released at Juneau’s hospital with minor injuries.
By Ed Silverman Nov. 30, 2015 Reprints Makary: We found that an increasing number of drugs approved by the FDA have been orphan drugs. Last year, seven out of 10 blockbuster drugs in the US were passed as orphan drugs, even though they’re used off-label for other conditions. There’s a time when, as physicians, we believe there’s a benefit to patients for an off-label use, and we should be able to give them the drug. The problem isn’t the off-label use. The problem is that some of these drugs may actually have been submitted [for FDA approval] with the ultimate intention for being used more broadly than if they were designed only for the rare disease populations. There’s a pattern of gaming the system to cash in on a taxpayer-funded benefit to the company, and it needs to be addressed in order to preserve the mission of the Act.Pharmalot: How do you mean ‘gaming the system?’Makary: So a rare disease population is defined as affecting less than 200,000 people. But what’s happening is that a drug company develops a medication to treat a specific cancer, and will submit that to the FDA as intended for a very targeted subset of the cancer population. For example, HER2-positive is most commonly associated with breast cancer, but is also found in other cancers. … Once a drug is approved, companies can seek additional indications for populations well exceeding 200,000 people. And this is a pattern with most of the orphan drugs approved by the FDA.Pharmalot: OK, but isn’t that a good thing if more patient populations are ultimately served?Makary: Any time a drug is approved by FDA to help patients, it should be celebrated. But if we create a special mechanism for a drug that ends up being more commonly used after approval, we believe there will be less research conducted for drugs for true orphan diseases. Companies will direct their efforts to wider populations. As a cancer doctor, there are patients that were being helped by the Act, but they may not be in the future.We think this law is being abused, because it suggests taxpayer-funded benefits are no longer truly concentrated on orphan diseases. These subsidies are provided by taxpayer dollars. Should taxpayers subsidize what may ultimately become blockbuster drugs? This is an especially important question, given the climate in America with outsized pricing. The median cost for orphan drugs is $98,534 per patient per year compared with a median cost of $5,153 per patient per year for drugs that are not approved for an orphan population. And the median cost of orphan drugs doubled between 2010 and 2014.Pharmalot: So what do you suggest?Makary: Drug companies should do what’s done in other countries, which is they should pay back the subsidies if their drug becomes a blockbuster. Perhaps a 1 percent tax if a drug grosses $1 billion a year. That seems to be a reasonable way to recoup the taxpayer-funded incentive, since those incentives were never intended for blockbusters. Or maybe if a drug is a $5 billion, the marketing exclusivity is shortened or the company pays a graduated tax.Right now, the public is frustrated with drug pricing. This is a good time to ask if we think the most vulnerable members of our society deserve products developed with some incentives for research and development. As a country, we’ve said the answer is ‘Yes,’ but we believe the mechanism should be re-evaluated.We’re the only country where our program to incentivize rare disease drug development has been abused to the point where 44 percent of all drugs approved, and seven out of 10 blockbuster drugs, are orphans. We hear about scientists asking how they can tailor a drug to gain an orphan indication. We shouldn’t have scientists talk about gaming systems. We want them talking about developing medications. Martin Makary, a cancer surgeon and professor of health policy at Johns Hopkins School of Medicine, is calling for reform to the Orphan Drug Act. Micah Kandros/Johns Hopkins School of Medicine In 1983, the Orphan Drug Act was passed to give drug makers incentives to create medicines for rare diseases, which are defined as maladies that affect fewer than 200,000 people. The incentives include tax credits and seven years of marketing exclusivity. Since then, more than 400 orphan drugs have been approved by the Food and Drug Administration. Last year, though, 41 percent of all FDA approvals were for orphan drugs. And sales of orphan medicines, which carry high price tags, are forecast this year to total $107 billion.In a new paper in the American Journal of Clinical Oncology, a team of researchers argues that drug makers are exploiting loopholes that allow them to widen the market for such drugs and distorting the original purpose of the law. We spoke with Martin Makary, a cancer surgeon and professor of health policy at Johns Hopkins School of Medicine, who is one of the authors, about the need for reform. This is an edited version of the conversation …Pharmalot: What’s the problem with the Orphan Drug Act?advertisement [email protected] Ed Silverman @Pharmalot About the Author Reprints PharmalotLaw for rare disease drugs needs revamping, researchers say Pharmalot Columnist, Senior Writer Ed covers the pharmaceutical industry. Makary: The dilemma is this: Pharmaceutical companies have invented and discovered cures for terrible medical conditions, which is wonderful, because generally, the research goes where the largest markets are. The Orphan Drug Act was passed in response to concerns that people with rare diseases were not getting any attention in the drug development community. It was intended to balance out this need with financial awards for companies that normally develop drugs that affect a large population. If we didn’t have the law, there’d be little incentive to develop drugs for rare conditions. Yet at the same time, there are unintended consequences, and this includes creating perverse incentives.Pharmalot: What do you mean by that, exactly?advertisement Tags FDAOrphan Drug Actrare diseases
Horizons ETFs launches global green bond fund Published in September, the framework defines eligible assets across seven green and four social project categories linked to the United Nations 2030 Agenda for Sustainable Development. Distribution of the bond was co-led by BMO Capital Markets. The offering closed on Oct. 21.In addition, the bank announced the development of an impact investment fund with $250 million in seed capital. Facebook LinkedIn Twitter Montreal-based BMO Financial Group introduced its first sustainability bond on Monday. The $500-million three-year Sustainability Bond will bear a fixed interest rate of 2.05% and will mature on Nov. 1, 2022. Proceeds of the bond will support eligible green and social asset categories as defined in the bank’s sustainable financing framework, a BMO release said. Related news Share this article and your comments with peers on social media 123RF IE Staff Keywords Green bondsCompanies BMO Financial Group You can’t afford to ignore sustainable finance CIBC enters green bond market
1,700 Young People Graduate from Heart Trust South -West Region UncategorizedDecember 10, 2006 Related1,700 Young People Graduate from Heart Trust South -West Region Advertisements Related1,700 Young People Graduate from Heart Trust South -West Region Related1,700 Young People Graduate from Heart Trust South -West Region FacebookTwitterWhatsAppEmail More than 1,700 young people on Thursday (Dec. 7) graduated from the HEART Trust/ NTA’s south-west region, with certification in some 35 skill areas.The graduates, from the Black River Vocational Training Centre, Ebony Park Academy, Enterprise Based Training, Mandeville Care Givers, and the Junction and Newport Vocational Training Centres, were presented with certificates in areas such as Business Administration, Data Operations, Electrical Installation, Garment Construction, Agro Food Processing and Ornamental Horticulture.Executive Director of the HEART TRUST/NTA Robert Gregory, in his remarks at the ceremony held at the Kendal Conference Centre in Manchester, told the students that their certification was “testimony to what you know and what you can do” and they must now display the attitude of “a trained, certified person”.He noted that HEART’s mission was to provide a trained Jamaican workforce, which was certified to international standards. The aim, he said, was to improve the country’s competitiveness in the regional and global economy. “All of you are players in the economy” Mr. Gregory told the graduates, noting that, “with your certification to international standards in whatever field you are working in, or have been trained, you are able to work everywhere in the world and compete with persons, who do a similar kind of job”.He added “you have succeeded, you have been assessed against these international standards and you have been proven competent so . that you are now receiving your certification. This is the visa of the 21st Century.”Executive Director of the Fair Trading Commission, Barbara Lee, who was the guest speaker at the function, congratulated the graduates on their achievement.She told them that they were now “a noble addition to the Jamaican workforce,” and they needed to “focus on what life is going to be like after the ceremony”.”Life is like a bank, you can’t take out what you don’t put in,” Mrs. Lee said, noting that they must now place focus on the key ingredients of learning, yearning and earning.The HEART TRUST/NTA trains approximately 11, 000 persons per year to meet the increasing demand for vocational skills.
Like australia, Canada banks on massive production tree planting for jobs and climate The Australian Government’s target for one billion new production trees, announced two years ago, has been emphatically endorsed today by news that Canada will spend $3.16 billion to plant an additional two (2) billion trees by 2030. Canada says it is a plan for meeting its climate change targets, as well as increasing the renewable resource used by the enormous Canadian timber sawmilling and processing industry.Canada’s Minister for Natural Resources, Seamus O’Regan said,“Planting two billion trees is more than a plan for climate action. It’s a plan for creating thousands of good, green jobs. We’re confronting the urgency of climate change and getting trees in the ground starting this spring.”Chief Executive Officer of the Australian Forest Products Association (AFPA) Ross Hampton said, “Canada’s forest industry is about twice as large as Australia’s, so the Australian Government’s one (1) billion new production tree planting target, which is half the scale of Canada’s, is not out of proportion. Both nations plan to plant all of these new trees by 2030.”“The difference between the countries is that whilst Canada is investing more than $3 billion in the program, in Australia, the Government is relying on creating the right conditions for private investment to achieve the growth needed. The most important action the Government can take is to ensure all the Regional Forestry Hubs around Australia are announced and enabled with start-up funding as soon as possible so that planning can take place to ensure the planting of the ‘right trees at the right scale in the right places’ (National Forest Industries Plan 2018 ‘Growing A Better Australia – A billion trees for jobs and growth‘ page 2).”“The second enabling activity is the modification of regulations to enable farmers, landowners and others to more easily access carbon credits obtained from the Emissions Reduction Fund (ERF) reverse auctions,” Mr Hampton said.“Assistant Minster for Forestry Jonno Duniam and Minister for Energy and Emissions Reduction Angus Taylor are to be congratulated for achieving some of these necessary changes already. It is vital that red tape reforms continue, and that pressure is brought on any States who are blocking the planting of new trees. It remains bizarre for example that in part of the largest tree growing area in Australia, the South West Victorian side of the Green Triangle, the Victorian government is yet to allow the Federal Government to declare the area exempt and deliver the carbon benefits of new trees to farmers and landowners,” Mr Hampton concluded.See 201215 Media Release – Canada 2 billion new trees final. /Public Release. This material comes from the originating organization and may be of a point-in-time nature, edited for clarity, style and length. View in full here. Why?Well, unlike many news organisations, we have no sponsors, no corporate or ideological interests. We don’t put up a paywall – we believe in free access to information of public interest. Media ownership in Australia is one of the most concentrated in the world (Learn more). Since the trend of consolidation is and has historically been upward, fewer and fewer individuals or organizations control increasing shares of the mass media in our country. According to independent assessment, about 98% of the media sector is held by three conglomerates. This tendency is not only totally unacceptable, but also to a degree frightening). Learn more hereWe endeavour to provide the community with real-time access to true unfiltered news firsthand from primary sources. It is a bumpy road with all sorties of difficulties. We can only achieve this goal together. Our website is open to any citizen journalists and organizations who want to contribute, publish high-quality insights or send media releases to improve public access to impartial information. You and we have the right to know, learn, read, hear what and how we deem appropriate.Your support is greatly appreciated. All donations are kept completely private and confidential.Thank you in advance!Tags:AFPA, Australia, Australian, Australian Government, climate change, Federal, federal government, Forestry, Government, Hampton, Investment, Media Release, Minister, production, red tape, renewable, resources
Share Share via TwitterShare via FacebookShare via LinkedInShare via E-mail Unusual spokes that appear fleetingly on the rings of Saturn only to disappear for years at a time may become visible again by July, according to a new study spearheaded by the University of Colorado at Boulder. The spokes, which are up to 6,000 miles long and 1,500 miles in width, were first spotted 26 years ago by the Voyager spacecraft, said CU-Boulder Professor Mihaly Horanyi of the Laboratory for Atmospheric and Space Physics. But when the Cassini spacecraft arrived at Saturn in July of 2004, the striking radial features that cut across Saturn’s ring plane were nowhere to be found — an event that disappointed and puzzled many scientists, he said. The Hubble Space Telescope occasionally observed the ring spokes in the late 1990s, said Horanyi, a professor of physics at CU-Boulder. But the spokes gradually faded, a result of Saturn’s seasonal, orbital motion and its tilted axis of rotation that altered the light-scattering geometry. “The spokes were switched off by the time Cassini arrived,” said Horanyi. “We think it is a seasonal phenomena related to the sun rising and setting over the ring plane that changes the physical environment there, making it either friendly or hostile to their formation.” A paper on the subject appears in the March 17 issue of Science magazine. The paper was authored by doctoral student Colin Mitchell and Horanyi of CU-Boulder’s LASP, Ove Havnes of the University of Trosmo in Norway and Carolyn Porco of the Space Science Institute in Boulder. The spokes are made up of tiny dust particles less than a micron in width – -about 1/50th the width of a human hair — that collect electrostatic charges in the plasma environment of the rings and become subject to electrical and magnetic forces, said Horanyi. The right conditions cause them to gain an extra electron, allowing them to leap en masse from the surface of ring debris for brief periods, collectively forming the giant spokes that appear dark against the lit side of the rings and bright against the unlit side of the rings. The researchers hypothesize that the conditions for the spokes to form are correlated to a decrease in the angle of the ring plane to the sun. “Because the rings are more open to the sun now than when Voyager flew by, the charging environment above the rings has prevented the formation of the spokes until very recently,” the researchers wrote in Science. Cassini first imaged a “puny version” of Saturn’s spoke rings from a distance of 98,000 miles in early September that were only about 2,200 miles in length and about 60 miles wide, said Horanyi. The team believes the spoke sighting may have been an “early bird” event. As the ring plane angle decreases when Saturn is near its two seasonal equinoxes, the conditions appear to become more suitable for the formation of the eerie spokes, said Horanyi. Although Cassini currently is orbiting too close to the ring plane to make observations, the researchers expect the spoke activity to have returned by the time the spacecraft increases its inclination in July 2006. Once the spokes are visible again, the research team believes there will be spoke activity for about eight years, based on the fact that it takes Saturn about 30 Earth-years to complete one orbit around the sun, said Horanyi. The eight-year period should be followed by about six-to-seven years of a spoke hiatus, he said. The dust grains levitated by plasma during spoke-forming periods are probably hovering less than 50 miles above the rings themselves and they scatter light from the sun differently than do the rings themselves, he said. But there are still many questions about the spokes, said Horanyi. “We don’t know if they form by rapidly expanding, or if they form all at once,” he said. During the Voyager mission, they were absent during one observation, but fully developed in a follow-up observation made just five minutes later, Horanyi said. “This is a weird phenomena; we don’t have the full story on it yet,” he said. Published: March 15, 2006
HomeNewsEducationSamohi student surprised with $40k scholarship Mar. 27, 2019 at 5:40 amEducationFeaturedGovernmentHigh SchoolNewsSamohi student surprised with $40k scholarshipAngel Carreras2 years agoantonio sheltonEdison Internationalhigh schoolKatie Richardsscholarship For most students, a trip to the principal’s office means trouble. Katie Richards, a 17-year-old Samohi senior, was thinking along the same lines after receiving a note summoning her to the office before she was greeted by friends, family and a $40,000 scholarship from Edison International.Richards was one of 30 students to receive a $40k scholarship from Edison International, who doles out $1.2 million in scholarships annually to students prepared to embark on a STEM-related career. To win the scholarship, she submitted a video to Edison detailing how she would help prevent powerline-caused fires in the area.When Richards arrived at the office, a flurry of clicking camera shutters snapped and whirred as shock spread across the Samohi senior’s face. Edison’s CEO greeted Richards with flowers and an oversized check while mom, grandparents, teachers, counselors and a friend clapped and cheered.“I was kind of shocked when I walked in,” Richards said, after the scholarship ceremony. “I had to leave early today, so I thought I filled out a form wrong or something. I thought maybe that’s why I was being called in. But this… is all… I’m still processing it.”With her newly earned scholarship money, Richards plans to attend the Stevens Institute of Technology, located in Hoboken, New Jersey. There she’ll develop her engineering skills, such as the skills she showed off to win Edison’s attention and a scholarship.Richards (with the help of some classmates) created a video displaying technology she was developing to be used to prevent wildfires. Her tech measures the relationship between power lines and humidity.“What we were making would detect arcing the moment it starts with sound heat and static electricity levels,” she said. “I think it’d help prevent fires like the ones we had this past year.”Richards made a point to thank everyone that supported her, including her high school which she says shaped her, academically and socially. If this surprise scholarship ceremony had happened freshman year, she says she would’ve cried from social anxiety. And if it weren’t for her teachers, she wouldn’t know the academic path she’d be taking right now.“The school … now [the scholarship] … this has all helped me in so many ways.”Samohi Principal Antonio Shelton says the feeling of appreciation is mutual.“We’re tremendously proud,” he said. “Oh yeah. One of the best things about this is she developed something that is relevant to what’s going on in society right now. She has played a role in the future and will enact change. That’s Samohi, that’s who our kids are and how we develop young people. We’re extremely proud of her and how she has represented us.”[email protected] :antonio sheltonEdison Internationalhigh schoolKatie Richardsscholarshipshare on Facebookshare on Twitteradd a commentAnother BoondoggleCalifornia may toughen immunization rules to block measlesYou Might Also LikeFeaturedNewsBobadilla rejects Santa Monica City Manager positionMatthew Hall8 hours agoFeaturedNewsDowntown grocery to become mixed use developmenteditor19 hours agoNewsBruised but unbowed, meme stock investors are back for moreAssociated Press19 hours agoNewsWedding boom is on in the US as vendors scramble to keep upAssociated Press19 hours agoNewsCouncil picks new City ManagerBrennon Dixson19 hours agoFeaturedNewsProtesting parents and Snapchat remain in disagreement over child protection policiesClara Harter19 hours ago
BELMONT, Mich. – Sandra Gal made six straight birdies on her back nine Thursday to take the first-round lead in the Meijer LPGA Classic, while Michelle Wie withdrew because of a wrist injury. Gal, the 29-year-old German who won her lone LPGA Tour title in 2011, birdied Nos. 3-8 and finished with a par on No. 9 for a 6-under 65 at Blythefield Country Club. ”I was in a zone, I was really relaxed,” Gal said. ”I was talking a lot to my caddie and to my playing partners, just kind of letting it happen instead of forcing it.” Wie was 5 over after nine holes when she pulled out. She fought injuries to both wrists in 2007. ”It just started hurting last week and kept getting worse,” Wie said in the parking lot outside the medical trailer. ”It got to the point where I really couldn’t hold a club today. I’m going to try and get an MRI right now and see what my next steps are. So we’ll see.” The U.S. Women’s Open winner in June for her second victory of the year, Wie said she hoped to be able to play next week in the LPGA Championship – the fourth major championship of the season. South Korea’s Inbee Park was a stroke behind Gal. Australia’s Katherine Kirk opened with a 67, and Azahara Munoz was another stroke back along with IIhee Lee, Katy Harris, Gerina Piller, Amy Young and Line Vedel. Second-ranked Lydia Ko, the 17-year-old star coming off a victory in the Marathon Classic in Sylvania, Ohio, matched Paula Creamer with a 69, and top-ranked Stacy Lewis shot 70. Gal played in the morning wave in the LPGA Tour’s first regular tournament in Michigan since the Oldsmobile Classic ended its nine-year run in East Lansing in 2000. Gal said her birdie run, which tied the best string on the tour this season, was a combination of hitting her iron shots inside 10 feet on each of the holes and then making solid putting strokes. ”You have to be on the right side of the hole to have chances at birdies and I was on the front nine,” she said. ”I like this old-style type course and the greens are perfect. There were no long putts, just solid ones after good iron shots and I hit a couple real close, like 3 or 4 feet. It was a little bit of everything.” Park has one victory this year after winning six times last season. ”Everything was working really well today, especially the iron shots,” she said. ”The greens are rolling really well, too. They’re rolling really true. I hit a lot of good putts so that’s giving me confidence going into the next three days.” Lewis, who has three wins and 13 top-10 finishes this year, said she played better than she scored. ”I’ve been working on a few things with my golf swing and was pretty happy actually with the way I hit it – just had a bunch of putts right over the edge,” Lewis said. ”Overall, pretty happy with it even though the score is not quite what I was looking for.” Ko had the same issue with putts just missing. ”The golf course is in great shape so the birdies are there to be made,” she said. ”I just didn’t make as many as I would have liked. I really like the way I’m playing, though.”
Legal Advocate Discusses Medical Abuse At Shut Down Georgia ICE Facility Cobb County’s Cumberland Community Improvement District (CID) is getting ready to grow by hundreds of acres, but the land will not be used for commercial development. Broadcast Version0:48With Tuesday’s approval by the Cobb Board of Commissioners, the Cumberland CID will soon add more than 570 acres to its boundaries; the acreage is part of the Chattahoochee River National Recreation Area.According to CID Chairman Tad Leithead, his organization will work with the National Park Service to make the area more user friendly according to CID Chairman Tad Leithead. “One of the things we’re focusing on is access into the park,” said Leithead. “And we’ll be focusing on trail systems within the park that allow people, pedestrians and bicyclists particularly, to experience more of the national park conveniently.”No money is changing hands, but the CID had to enter into the agreement with the National Park Service in order to spend money for improvements. Leithead says there are no specific projects planned yet. Share Related Stories ‘It’s Fractured’: Georgia Lt. Gov. Geoff Duncan On Healing Republican Party For Whom The Bell Rings 0:48 | Play story Add to My ListIn My List
+1 ← Apply for TC for Youth Leaders of the African Diaspora Living in Europe Volunteer Judge for the Queen’s Commonwealth Essay Competition 2021 The Royal Horticultural Society Photographic Competition Leave a Reply Cancel ReplyYou must be logged in to post a comment. Deadline: 15 November 2015Open to: youth aged between 13-15 worldwidePrizes: participation in the 2016 Global Youth Eco-Leadership SummitDescriptionSamsung Engineering offers opportunities to the young students (aged 13-15) to participate in the 2016 Global Youth Eco-Leadership Summit (GYELS) which is the biggest global environment forum for youth in Korea. To participate in this competition you have to write essay (200 words) about the Future of Energy and Young People.EligibilityYouth aged 13-15 worldwide;Applicants who live in Thailand, Saudi Arabia and India must apply for the local competition. Otherwise, submitted applications to wrong category will not be considered.PrizesSix winners of the competition representing each country will be given the opportunities to participate in the 2016 Global Youth Eco-Leadership Summit which program includes Global Youth for the Environment Forum, Model United Nations and excursions in Seoul, Korea in order to advance their awareness, role and commitment for the environmental conservation and protection. The trip to 2016 GYELS in Korea will be in February 2016 and will be fully sponsored by Samsung Engineering.How to apply?For successful application you have to register on the official web-page. The guideline how to register and submit your essay and CV is available HERE.For more information, please visit official web-page. Tweet Reddit October 8, 2015 Published by michal LinkedIn 0 Similar Stories Share 0 Eco-generation Environmental Leadership Competition Pocket The Masters Review Flash Fiction Contest 2021 Three Tips on How to Get an Internship in International Development →